5. Joint research project : Biological vulnerabilities: Risk evaluation, ultra-fast detection and identification of agents relevant in terms of bio terrorism (BIGRUDI)


Funding code: 13N9592

A joint research project funded by the BMBF (Federal Ministry of Education and Research) aiming at the combination of existing individual analyses for BT agents into an automatable, mulitplex capable and mobile detection system. Combined with spectroscopic detection methods the intention is to create a diagnostic platform allowing simultaneous, fast and sensitive detection of BT relevant agents also for non-specialist personnel (first responders).
Objective of GenExpress's subproject is the recombinant expression of bacterial, viral and toxic proteins for antibody and aptamer production.


Project partners associated with GenExpress:

Federal Office for Civil Protection and Disaster Assistance

Bundesamt für Bevölkerungsschutz und Katastrophenhilfe (BBK), Bonn

Federal Office of Criminal Investigation

Bundeskriminalamt (BKA), Wiesbaden

State Office of health Baden-Wuerttemberg

Landesgesundheitsamt Baden-Württemberg (LGA), Stuttgart

Jenoptik Instruments GmbH, Jena

Scienion AG, Berlin

Technical University of Berlin, Institute of biotechnology

Technische Universität Berlin, Insitut für Biotechnologie

FZMB GmbH, Bad Langensalza

Freie Universität Berlin, Institute of biotechnology and biochemistry

Freie Universität Berlin, Institut für Biotechnologie und Biochemie

Charité, Institute of pharmacology, Berlin

Charité, Institut für Pharmakologie, Berlin

University of advanced science Wildau, bio-systems engineering

Technische Fachhochschule Wildau (TFHW), Biosystemtechnik

Robert Koch-Institut (RKI), Berlin

Philipps-University Marburg, Institute of virology

Philipps-Universität Marburg, Institut für Virologie


Final report_13N9592german.pdf (317 KB)

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